Panadol Advance use – Panadol Blue
Panadol is a pain reliever drug that relieves different degrees of pain according to the type and nature of pain The speed of analgesia provided by Panadol varies, and it is antipyretic. It can be used while driving.
Panadol types
The Panadol family includes a variety of analgesics, all of which contain paracetamol as the main substance. The types of Panadol can be divided into:
- Daily pain relievers: These include Panadol Advance (Panadol Blue).
- Rapid-acting analgesic (Panadol Extra, Panadol Migraine).
- Cold and Flu Relief (Panadol Cold + Flu .)
- Severe pain reliever (Panadol extxa).
- Joint pain reliever (Panadol Joint)
- Menstrual pain reliever (Panadol woman).
Note: Some models are not available in all countries.
What is Panadol Advance?
Panadol Advance is a tablet used to treat mild to moderate pain such as headache, menstrual pain, toothache and arthritis. It also helps reduce fever because it contains Paracetamol.
Paracetamol generally takes up to an hour to work, and in two studies of patients with dental pain, pain relief was observed to take an average of 15 minutes after giving a dose of 1000 mg of Panadol tablets, as for Panadol Advance with Optizorb technology. According to the manufacturer, it is designed to be absorbed within 5 minutes.
Panadol Advance Ingredients
The active substance in Panadol Advance is: Paracetamol at a concentration of 500 mg.
Inside the disc contains:
- Magnesium Stearate
- wet starch
- Distilled water
- Calcium carbonate
- alginic acid
- crospovidone
- Povidone (K-25)
- Anhydrous colloidal silica
The outer cover of the disc consists of:
- carnauba wax
- Distilled water
Panadol Advance dosage
- For children aged 6 to 12 years, half to one tablet can be taken daily, taking care not to give the child more than 4 tablets in 24 hours.
- For people over 12 years old, take 1 to 2 tablets every 4 to 6 hours. Adults should not give more than 8 tablets in 24 hours.
- When taking Panadol, do not crush the tablet, because crushing it may cause it to be absorbed faster than usual.
Contraindications to the use of Panadol Advance
Panadol Advance should not be used in patients with hypersensitivity to paracetamol. Children should not be given Panadol Advance 500 mg Tablets for longer than 3 days without consulting a doctor. Patients who suffer from arthritis and need to take painkillers every day should consult their doctor before using Panadol Advance for a long time. Caution should be exercised in patients with glutathione depletion states, as the use of paracetamol may increase the risk of developing metabolic acidosis (a condition that causes high acidity of the blood and body).
Paracetamol increases the effect of anti-blood-clotting medicines if it is used for long periods and regularly, and this increases the risk of bleeding, so you should ask your doctor before taking any of these medicines in conjunction with taking Panadol.
Consult your doctor if you take too much Panadol Advance, even if you feel fine because taking too much paracetamol can damage your liver.
Do not take any other medicinal product containing paracetamol while taking Panadol Advance.
Panadol Advance drug interactions
- Metoclopramide or domperidone can increase how quickly Panadol is absorbed.
- Colestyramine compounds can reduce its absorption.
- Taking Panadol Advance during pregnancy and lactation
- Studies on the neurodevelopment of fetuses exposed to paracetamol in utero show unclear results, so Panadol Advance can be used during pregnancy and breastfeeding, but it should be taken at the lowest dose for the shortest possible period.
Panadol Advance side effects
The use of Panadol Advance to treat temporary pain has no significant side effects, and some clinical trials have found that the side effects of Panadol Advance are rare, and there are some serious but very rare effects such as:
- bronchospasm
- thrombocytopenia
- Cutaneous hypersensitivity reactions including rash and angioedema.
Panadol Advance overdose
This drug from Panadol Advance or Paracetamol may have serious harm as it can lead to liver failure, and this harm can happen to adults if they take a dose of 10g or more of Paracetamol, and if the patient has risk factors for liver disease, taking 5g may lead From paracetamol to liver damage.
Symptoms of an overdose of Panadol Advance
During the first 24 hours of taking the drug overdose, the patient may show some signs, including:
- paleness
- Nausea and vomiting.
- Anorexia.
- Abdominal pain.
Liver damage may occur after 12 to 48 hours, and in cases of severe poisoning, liver failure may develop into encephalopathy, bleeding and hypoglycemia.
Liver damage may not occur, but an overdose can lead to an irregular heartbeat and inflammation of the pancreasIf the patient takes an overdose of paracetamol, he should get immediate treatment even before symptoms appear, so he must be referred immediately to the hospital, and symptoms may be limited to nausea and vomiting and do not develop further than that.
The patient can be given activated charcoal if he has taken an overdose of the drug within one hour, and the concentration of paracetamol in the blood must be measured 4 hours after taking the drug because its measurement before that will not be documented.
The difference between blue and red panadol
Panadol Advance is known as Panadol Blue, while Panadol Extra is known as Panadol Red, and both types contain paracetamol as an active substance, but the difference between the two types is:
Panadol Red contains caffeine with 65 mg caffeine. Equipped with technology that makes it faster to absorb as it starts working in 10 minutes, while Panadol Blue may take up to an hour to start working (But a new formulation of Panadol Advance Blue called opti zorb was provided and it was announced that it was absorbed in just 5 minutes) .Panadol Red relieves moderate and mild pain, while Panadol Red helps relieve severe pain such as muscle and joint pain, toothache and also helps treat symptoms caused by colds, flu, headaches, migraines and menstrual pain in women.
Panadol Blue can be given to children from 6 years of age at a lower dose than the adult dose, while Panadol Red is not recommended for children under 12 years of age.
Conditions for storing and storing Panadol Advance
- Store Panadol Advance away from moisture and at temperature below 30°C.
- Medicines should be kept out of the reach of children.
- All the contents of the article, including pictures and information, are from the source: Al-Morsal.
